Today, the latest Imfact Factor for scientific journals has been released out by Thomson Reuters’s JCR report. As China’s leading journal in the life sciences, Cell Research harvested its credit 8.151. A Rocket-jumping from around 5.
Cell Research is run by Institute of Biochemistry and Cell Biology in China, Dr. Dangsheng Li as chief editor, previous Associate Editor of Cell.
As mentioned in one previous post, Dr. Li also started another peer-reviewed journal Journal of Molecular Cell Biology (JMCB) last year. Definitely, Cell Research and “the new launch of JMCB will greatly promote the communications and exchanges of big-bang-ideas between Chinese and international biological scientists.”
Tags: Cell Research·impact factor
After the open access journal PLoS ONE being indexed by Web of Science at the begin of 2010, PLoS ONE will harvest a full report of citation metrics from 2009 Journal Citation Reports®, although PLoS Says NO to journal impact factor and “focus efforts on more sophisticated, flexible and meaningful measures”.
Nevertheless, its journal impact factor will be available in June 2010.
The rough estimate of PLoS ONE impact factor is 5-7. Wait and See!
UPDATED:
Finally, the latest impact factor for PLoS One is released out with 4.351, a bit far from the earlier estimate.
Cheers!
Tags: impact factor·PLoS ONE
The latest JCR ISI Journal Impact Factor 2010 (actually the Impact Factor 2009) is coming during June.
The journal Impact Factor 2010 is based on the previous two-year average citations per published research paper.
Tags: impact factor
A latest research paper in Genes Dev. by the NIBS group of Dr. Xi RW from China:
Genes Dev. 2010 May;24(9):933-46.
Polycomb group genes Psc and Su(z)2 restrict follicle stem cell self-renewal and extrusion by controlling canonical and noncanonical Wnt signaling.
Li X, Han Y, Xi R.
National Institute of Biological Sciences, Beijing 102206, People’s Republic of China.
Abstract
Stem cells are critical for maintaining tissue homeostasis and are commonly governed by their niche microenvironment, although the intrinsic mechanisms controlling their multipotency are poorly understood. Polycomb group (PcG) genes are epigenetic silencers, and have emerged recently as important players in maintaining stem cell multipotency by preventing the initiation of differentiation programs. Here we describe an unexpected role of specific PcG genes in allowing adult stem cell differentiation and preventing stem cell-derived tumor development. We show that Posterior sex combs (Psc), which encodes a core Polycomb-repressive complex 1 (PRC1) component, functions redundantly with a similar gene, Suppressor of zeste two [Su(z)2], to restrict follicle stem cell (FSC) self-renewal in the Drosophila ovary. FSCs carrying deletion mutations of both genes extrude basally from the epithelium and continue to self-propagate at ectopic sites, leading to the development of FSC-like tumors. Furthermore, we show that the propagation of the mutant cells is driven by sustained activation of the canonical Wnt signaling pathway, which is essential for FSC self-renewal, whereas the epithelial extrusion is mediated through the planar cell polarity pathway. This study reveals a novel mechanism of epithelial extrusion, and indicates a novel role of polycomb function in allowing adult stem cell differentiation by antagonizing self-renewal programs. Given evolutionary conservation of PcG genes from Drosophila to mammals, they could have similar functions in mammalian stem cells and cancer.
Tags: Stem Cell
PubAlert is initially produced for my convenience, mainly covering journals in the developmental biology field. Still it’s publicly accessible, for you!
What’s PubAlert all about?
PubAlert ( http://pub.genedog.org/ )is a free and non-profit online aggregator service that functions to track the scientific journals and bring together the up-to-date research articles all into one channel. So you can stay alerted to new research publications by visiting PubAlert on a regular basis.
Check it out!
Tags: PubAlert·Research Publication·Scientific Journal·Scientific Publication
There are some readers asking, “How do I find the impact factor for a journal?”…hmmm…Before answering this issue, you should be noticed that, this blog DONOT distribute the impact factor list in any format (pdf, excel/xls, word/doc, etc).
However, you can check information on impact factor of your favorite scientific journals in the following ways:
- Check ISI Web of Knowledge with a new session if necessary at http://admin-apps.isiknowledge.com/JCR/JCR to get the up-to-date sci impact factor scores of 2008/2009 journal ranking performance.
- Google it! Generally, you can get the necessary impact factor information at the official website of the corresponding journals!
Check it out by yourself~ 
2010.03.16
Tags: impact factor
As we all know, loss in the ability to hear or discriminate sounds clearly is a common disability, which will cause the patients to be depressed and suffer from the quality of life. If temporarily there is no cure for the hearing loss, hearing aids may help to improve your hearing. Cochlear implant, an electronic device created utilizing the advances in techonogy, is such a solution of hearing aid for children and adults who have hearing problems.
[Read more →]
Tags: Cochlear implant·hearing loss
Year 2010 is around so quick, GeneDog Blog wishes every reader a happy new year 2010! In the Chinese calendar, 2010 is the year of the Tiger, which has a meaning of power and braveness. So, let us go ahead, and expect lots of more interesting and fascinating unknowns and bright future.
Tags: 2010·New Year
A recent Nature paper reports a genome wide RNAi screen targeting the potential Drosophila apoptotic effectors in apoptosis pathway hopefully to further our understanding of the conserved machanisms underlying PCD.
Pubmed abstract:
Nature. 2009 Jul 2;460(7251):123-7. Epub 2009 May 31.
Genome-wide silencing in Drosophila captures conserved apoptotic effectors.
Chew SK, Chen P, Link N, Galindo KA, Pogue K, Abrams JM.
Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.
Apoptosis is a conserved form of programmed cell death firmly established in the aetiology, pathogenesis and treatment of many human diseases. Central to the core machinery of apoptosis are the caspases and their proximal regulators. Current models for caspase control involve a balance of opposing elements, with variable contributions from positive and negative regulators among different cell types and species. To advance a comprehensive view of components that support caspase-dependent cell death, we conducted a genome-wide silencing screen in the Drosophila model. Our strategy used a library of double-stranded RNAs together with a chemical antagonist of Inhibitor of apoptosis proteins (IAPs) that simulates the action of native regulators in the Reaper and Smac (also known as Diablo) families. Here we present a highly validated set of targets that is necessary for death provoked by several stimuli. Among these, Tango7 is identified as a new effector. Cells depleted for this gene resisted apoptosis at a step before the induction of effector caspase activity, and the directed silencing of Tango7 in Drosophila prevented caspase-dependent programmed cell death. Unlike known apoptosis regulators in this model system, Tango7 activity did not influence stimulus-dependent loss of Drosophila DIAP1 (also known as th and IAP1), but instead regulated levels of the apical caspase Dronc (Nc). Similarly, the human Tango7 counterpart, PCID1 (also known as EIF3M), impinged on caspase 9, revealing a new regulatory axis affecting the apoptosome.
Tags: apoptosis·apoptosis pathway·Drosophila·Drosophila RNAi screen·genome wide screen·RNA interference·RNAi·RNAi silencing
Charles Darwin’s Evolution Theory of Life Summarized by ONE Cartoon
It is well known that Charles Darwin’s evolution theory of life presents a trend and direction of life’s evolution from prokaryotic to eukaryotic cells, from invertebrate to vertebrate, from simple to complex, etc.
Before showing you the amazing cartoon astonishingly elucidating the thread of the evolution of life, let’s take a look at Darwin’s rudimentary describing of the theory of evolution:
Charles Darwin wrote:
“THE AFFINITIES of all the beings of the same class have sometimes been represented by a great tree. I believe this simile largely speaks the truth. The green and budding twigs may represent existing species; and those produced during each former year may represent the long succession of extinct species . . . The limbs divided into great branches, and these into lesser and lesser branches, were themselves once, when the tree was small, budding twigs; and this connexion of the former and present buds by ramifying branches may well represent the classification of all extinct and living species in groups subordinate to groups . . . From the first growth of the tree, many a limb and branch has decayed and dropped off, and these lost branches of various sizes may represent those whole orders, families, and genera which have now no living representatives, and which are known to us only from having been found in a fossil state . . . As buds give rise by growth to fresh buds, and these, if vigorous, branch out and overtop on all a feebler branch, so by generation I believe it has been with the Tree of Life, which fills with its dead and broken branches the crust of the earth, and covers the surface with its ever branching and beautiful ramifications” (Darwin, 1859).
Well, it is the right time to present you the amazing cartoon summarizing the evolution of life, including YOU!
Tags: darwin evolution·darwin's theory of evolution·evolution·evolution theory·evolution video·life evolution
