A latest PNAS paper reporting that Lsd1, the histone lysine-specific demethylase 1, play roles in the niche of female germline stem cells and may nonautonomously affect germ cell via niche cell related signals. – GeneDog
Proc Natl Acad Sci U S A. 2011 Apr 11. [Epub ahead of print]
Loss of lysine-specific demethylase 1 nonautonomously causes stem [...]
Entries Tagged as 'Stem Cell'
Loss of lysine-specific demethylase 1 nonautonomously causes stem cell tumors in the Drosophila ovary
April 17th, 2011 · No Comments · Stem Cell
Tags:
Ecdysteroids affect Drosophila ovarian stem cell niche formation and early germline differentiation
March 28th, 2011 · 1 Comment · Stem Cell
A latest article of EMBO J showing the role of ecdysone signalling in the regulation of female Drosophila GSC niche size.
It is interesting to see another related research about ecdysone and GSC control (link).
EMBO J. 2011 Mar 18. [Epub ahead of print]
Ecdysteroids affect Drosophila ovarian stem cell niche formation and early germline differentiation.
König A, Yatsenko [...]
Tags:
The Fused/Smurf Complex Controls the Fate of Drosophila Germline Stem Cells by Generating a Gradient BMP Response
December 12th, 2010 · 1 Comment · Stem Cell
A latest article in Cell, reports the Fused/Smurf complex in the shaping of the BMP gradient in the control of female GSC fate regulation in Drosophila. This work is done by Dr. Chen DH group at Institute of Zoology, Chinese Academy of Sciences, China. Congrats to all the authors! – GeneDog
Incoming search terms:BMP Smurfcell 10 [...]
Tags:
In and Out: steroid hormone and chromatin remodelling factors in female Drosophila GSC
November 4th, 2010 · No Comments · Stem Cell
A latest article in Cell Stem Cell by Dr. Drummond-Barbosa Group in Vanderbilt University Medical Center, reports that the systemic factor ecdysone, a steroid hormone, and ISWI / Nurf301 act together to regulate the female GSC self-renewal and proliferation independently of insulin signaling in Drosophila. It broadens our view of the mechanisms underlying GSC regulation [...]
Tags: Drosophila·Germline Stem Cell
Link between Germline Stem Cell Maintenance and Lifespan Extension by Dietary Restriction?
October 25th, 2010 · No Comments · Stem Cell
It is well-known that lifespan is extended under dietary restriction (DR) to overcome the growth disadvantage. However, the underlying mechanisms remain largely unknown. A latest short article in Aging Cell reveals a potential link between lifespan and germline stem cell (GSC) in male Drosophila. – GeneDog
Aging Cell. 2010 Oct;9(5):916-8.
Dietary restriction enhances germline stem cell maintenance.
Mair [...]
PcG genes restrict Drosophila follicle stem cell (FSC) growth
May 9th, 2010 · No Comments · Stem Cell
A latest research paper in Genes Dev. by the NIBS group of Dr. Xi RW from China:
Genes Dev. 2010 May;24(9):933-46.
Polycomb group genes Psc and Su(z)2 restrict follicle stem cell self-renewal and extrusion by controlling canonical and noncanonical Wnt signaling.
Li X, Han Y, Xi R.
National Institute of Biological Sciences, Beijing 102206, People’s Republic of China.
Abstract
Stem cells [...]
Tags: Stem Cell
