A latest article in Cell Stem Cell by Dr. Drummond-Barbosa Group in Vanderbilt University Medical Center, reports that the systemic factor ecdysone, a steroid hormone, and ISWI / Nurf301 act together to regulate the female GSC self-renewal and proliferation independently of insulin signaling in Drosophila. It broadens our view of the mechanisms underlying GSC regulation [...]
Entries Tagged as 'Drosophila'
In and Out: steroid hormone and chromatin remodelling factors in female Drosophila GSC
November 4th, 2010 · No Comments · Stem Cell
Tags: Drosophila·Germline Stem Cell
Drosophila genome wide RNA interference screen of apoptosis pathway
August 11th, 2009 · No Comments · RNAi, uncategorized
A recent Nature paper reports a genome wide RNAi screen targeting the potential Drosophila apoptotic effectors in apoptosis pathway hopefully to further our understanding of the conserved machanisms underlying PCD.
Pubmed abstract:
Nature. 2009 Jul 2;460(7251):123-7. Epub 2009 May 31.
Genome-wide silencing in Drosophila captures conserved apoptotic effectors.
Chew SK, Chen P, Link N, Galindo KA, Pogue K, Abrams [...]
Tags: apoptosis·apoptosis pathway·Drosophila·Drosophila RNAi screen·genome wide screen·RNA interference·RNAi·RNAi silencing
